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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 25-year-old man who weighs 80 kg is brought to the emergency department following a motor vehicle collision. He has severe facial contusions and a presumed closed head injury. His Glasgow Coma Scale score is 8. An emergency CT scan shows no evidence of intracranial bleeding. What should recommendations for therapy include?

A) Diazepam 5 mg intravenously over 5 minutes, qh6 for one week
B) Phenytoin 1,200 mg intravenously over 45 minutes, then an appropriate maintenance dose for one week
C) Fosphenytoin 25 PE/kg intravenous push, then an appropriate maintenance dose for one week
D) Dexamethasone 10 mg intravenously q6h for one week

2. A patient with a COPD exacerbation is treated with prednisone 40 mg daily for one week with improvement. To discontinue the prednisone, the most appropriate procedure would be which of the following?

A) Reducing the daily prednisone dose by 25% every day until the patient is off the drug.
B) Stopping prednisone administration without dose tapering.
C) Reducing the daily prednisone dose by 50% every other day until it is down to 10 mg daily, then reducing it by 25% every other day until the patient is off the drug.
D) Reducing the daily prednisone dose by 50% every day until the patient is off the drug.

3. Which statement best describes current recommendations on postnatal corticosteroids in neonatal Broncho pulmonary dysplasia?

A) Late and long-term hydrocortisone therapy may be warranted.
B) Combination of dexamethasone and hydrocortisone long-term therapies is advised.
C) High-dose dexamethasone is routinely and strongly recommended.
D) Early, low-dose, short-course hydrocortisone therapy may be beneficial.

4. A 72-year-old man has chronic insomnia that has not responded to measures to improve sleep hygiene. The patient is not depressed and has no other chronic health problems. It is determined that medication use will probably be necessary to manage the insomnia. What is the best initial recommendation for this patient?

A) Alprazolam
B) Trazodone
C) Amitriptyline
D) Diphenhydramine

5. A 24-year-old Woman complains of dysuria, hesitancy in urination, and frequent urination for the past 2 days. She has no costovertebral tenderness, fever, or history of UTls. Urinalysis data are:
* pH: 5.5
* WBCS: 15 cells/ul
* RBCS:5 Cells/uL
* Bacteria: Numerous Gram-negative rods
* Negative for protein, glucose, and WBC casts
For this patient, assuming that local resistance rates are low, which of the following would be an empiric cost-effective regimen?

A) Sulfamethoxazole/trimethoprim one double-strength tablet twice daily for 3 days
B) Azithromycin 1 g single dose
C) Ciprofloxacin 500mg twice daily for 7 days
D) Amoxicillin 500 mg three times daily for 7 days

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